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Description
The activation of specific signaling pathways, including Wnt, PI3K/AKT, Hedgehog, and NOTCH, contributes to the maintenance of quiescence in LSCs
Cadmium-Induced Pathologies: Where Is the Oxidative Balance Lost (Or Not)
RTA v.3)
Accordingly, macrophages are dependent upon extracellular sources of glutamine [6, 48]
Additionally, DA quinones can be oxidized to aminochrome, whose redox-cycling leads to the generation of the superoxide radical and the depletion of cellular nicotinamide adenine dinucleotide phosphate-oxidase (NADPH), which ultimately forms the neuromelanin (Sulzer et al., 2000) known to be accumulated in the SNpc of the human brain (Ohtsuka et al., 2013, 2014
