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Limitation: direct measurement of intracellular NAD+ in different tissues in humans is technically challenging
Henry FE, Wang X, Serrano D, Perez AS, Carruthers CJL, Stuenkel EL, Sutton MA (2018) A unique homeostatic signaling pathway links synaptic inactivity to postsynaptic mTORC1
Deficiency symptoms like fatigue, weakness, and decreased endurance directly impair athletic performance
Still, researchers with active malignancy are generally advised to avoid telomerase-activating compounds until more definitive safety data becomes available
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