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10.1111/cpr.12472 Cell Prolif

The treatment of aged rats with an inhibitor of iNOS or the use of GSNO in vitro demonstrated that SIRT1 is inhibited by S-nitrosylation and this results in p53 and NF-B increased activity with consequent production of pro-inflammatory cytokines [99]

Preferential cancer cell self-recognition and tumor self-targeting by coating nanoparticles with homotypic cancer cell membranes

Furthermore, side effects such as dose limitations and cardiotoxicity have significantly restricted their clinical application (5)

It is clear that there is a correlation between the pathology and the levels of LPO markers, but their role in the pathogenesis of these diseases is not clear
