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Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium

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Supplementary Figure S3 Gene expression levels for cytotoxic T-lymphocyte associated protein 4 ( CTLA4 ), arginase 2 ( ARG2 ), solute carrier family 16 member 6 ( SLC16A6 ), and lysine demethylase 6B ( KDM6B ) among treatment groups

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While it must be converted by the body into active coenzyme forms, its unique molecular structure makes it incredibly valuable in its own right