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Patients were randomized to receive pemetrexed 500 mg/m2 intravenously or docetaxel 75 mg/m2 as a 1-hour intravenous infusion once every 21 days
doi: 10.1016/j.clinre.2015.03.005
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Patients have been "tanked up" with daily injections, followed by weekly and then periodic ones that may continue the rest of their lives
