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Experimental design Healthy and diseased free Laca mice of either sex (34 months old, weighing 2530 g) were procured from the Central Animal House (CAH), Panjab University, and used in the present study

When 200 M copper, a concentration that did not cause overt neuronal toxicity, was applied to primary hippocampal neurons exposed to excitotoxic levels of glutamate/glycine, it completely abrogated cell death

10.1016/0006-2952(89)90048-8 Glazenburg EJ, Jekel-Halsema IM, Scholtens E, Baars AJ, Mulder GJ: Effects of variation in the dietary supply of cysteine and methionine on liver concentration of glutathione and "active sulfate" (PAPS) and serum levels of sulfate, cystine, methionine and taurine: relation to the metabolism of acetaminophen

In addition, CR6-interacting Factor 1 (CRIF1), also known as growth arrest and DNA damage-inducible proteins-interacting protein 1 (GADD45GIP1), interacts with Neh2 domain and the C-terminal region containing Neh1 and Neh3 of NRF2 to promote NRF2 ubiquitylation and degradation in a redox-independent manner [22]

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