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The skin also had visible unevenness due to acne and acne scars

Superimposition of the hTrx1 structures obtained in the hTrxR1hTrx1 complexes with published structures in the uncomplexed form (PDB codes 2hsh 18 , and 1aiu 17 ) also shows r.m.s

An experimental compound called ferrostatin-1, which blocks the iron-driven lipid damage at the heart of ferroptosis, substantially reduced that vulnerability and rescued cell viability under lab conditions, confirming that lipid damage is central to the mechanism
