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GLP-1 activation suppresses appetite and slows gastric emptying, while GIP signaling is thought to enhance energy expenditure, improve insulin sensitivity in adipose tissue, and reduce gastrointestinal side effects through central mechanisms

The risk of chronic diseases and death increases

Authors contributions Xiaoning Wang carried out the studies, participated in collecting data, and drafted the manuscript

Because no separately identifiable E/M service was performed, no E/M code is reported

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