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Also, gingipains of BEMNs stimulate endothelial release of interferon- (IFN-), which induces expression of the B7-H1 receptor on the surface of monocytes, T cells and B cells and that leads to the cell-mediated immune response

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supervision, A.U

Less common effects are reviewed at intake and during follow-up

Injection technique: Clean the injection site with an alcohol swab and allow to dry Pinch a fold of skin at the abdomen (avoiding 2 inches around navel), thigh, or upper arm Insert needle at 45-90 degree angle into the skin fold Inject slowly and steadily Withdraw needle and apply light pressure if needed Rotate injection sites systematically to prevent tissue irritation or lipohypertrophy