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We also included sperm DNA damage and adverse events such as side effects and miscarriage as secondary outcomes

Another study has reported that AC exerted protective effect against ulcerative colitis in mice via regulation of the HO-1/HMGB1 signaling pathway where the alterations in MDA, CAT, GSH, and SOD were clearly improved after treatment with 60 mg/kg intraperitoneal injection of AC for seven consecutive days (Guo et al

& Nagy, P

Slesak et al

Recently, with in-depth studies into kidney diseases and cell death, a new iron-dependent cell death modality, known as ferroptosis, has been identified and has attracted considerable attention among researchers in the pathogenesis of kidney diseases and therapeutics to treat them