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This suggests that grape seed extract may suppress the aberrant blood vessel growth observed in wet AMD

10.1016/j.idairyj.2006.06.015 14

Batterham RL, Le Roux CW, Cohen MA, Park AJ, Ellis SM, Patterson M, et al

Parvanova et al

Thus, in the absence of a healthy glycocalyx, excess sodium ions enter endothelial cells and activate cell signaling pathways that positively regulate production of F-actin cytoskeletal fibers (85)
