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Safety and efficacy of continuous subcutaneous foslevodopafoscarbidopa in patients with advanced Parkinsons disease: a randomised, double-blind, active-controlled, phase 3 trial

Low energy, tiredness and brain fog that has not responded to lifestyle changes Vegetarians and vegans who do not get B12 from animal foods Patients with absorption issues such as IBS, coeliac disease or pernicious anaemia, with appropriate GP oversight Anyone on long-term metformin or proton-pump inhibitors that lower B12 absorption Older adults whose stomach acid has dropped with age Patients looking for mood, focus and recovery support alongside a balanced diet Aftercare For the first forty-eight hours

Follow-up: When B12 therapy is initiated, you must check your energy state and nerve symptoms as well as laboratory measurements of B12, MMA, and homocysteine to determine progress

10.1016/S0165-2427(98)00111-1