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However, for the last several years, B12 injections have been given to people without clinical deficiencies

The research and formulation guidance converge on specific ranges that balance efficacy with safety

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Peripherally, pancytopenia is most often observed, but only 1-2 of the major cell types (erythrocytes, leukocytes, platelets) may be depressed in some cases

Further Reading For additional peer-reviewed research, see: NNMT inhibitor preclinical study by Neelakantan et al