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The Cys 38 and Cys 83 residues are also possibly involved in intermolecular disulfide bonds, as observed crystallographically (233)

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5,16,17,32 Besides their direct hydrolytic and cytotoxic effects upon the cells observed in vitro , the pathogenic mechanisms involved in SLE include the induction of initial lesions via deposition of circulating immune complexes (composed of lupus DNA and antibodies bound to it) in the tissues of various organs in vivo

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Glx was not related to symptomatology

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BPC 157 therapy counteracted both early and delayed neural hippocampal damage

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10.1161/CIRCRESAHA.110.237420 45

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