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The presence of diabetes and hyperglycemia tends to shift monocytes towards a functionally proinflammatory phenotype, which induces chronic inflammation and insufficient M2 functional profibrotic TGF- signaling [29] similar to that seen in G6PD-deficient subjects

Mol Metab 20 , 5162 (2019)

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Santos MC, Oliveira AL, Viegas-Crespo AM, et al

Finally, we showed that the functional enrichment analysis of Pc binding genes (e.g., per , tim ) is in agreement with previous phenotypic studies of these two circadian rhythm-related genes (Yang & Sehgal, 2001)
