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1985 May;17(5):48593

N-acetylcysteine and exacerbations of chronic obstructive pulmonary disease

Overactivated M1 macrophages exacerbate inflammation through secreting pro-inflammatory cytokines, driving joint damage, whereas immunosuppressive M2 macrophages are diminished, disrupting immune equilibrium (130)

Patients with renal disease who undergo hemodialysis are at risk for secondary carnitine deficiency because hemodialysis removes carnitine from the blood (see End-stage renal disease) (38)
