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This usually takes seconds and involves minimal discomfort

N., Zumbrennen, K
Clinical studies, such as the DAPA-CKD trial, have documented the efficacy of SGLT2 inhibitors in enhancing kidney function in non-diabetic patients 6

Nov 2014;39(11):1237-44

In a previous Phase I trial, six patients treated with a single dose of NTLA-2001 showed significant reductions in serum TTR protein levels, with no serious adverse effects or liver damage reported