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Sensitivity to cobalt and/or Vitamin B12 is a contraindication Clients with chronic liver and/or kidney dysfunction, Lebars disease (hereditary eye disease) or abnormal red blood cells (megaloblastic anaemia) should not take frequent B12 injections

Copper induces oxidative stress and H 2 O 2 production in HepG2 ATP7B-KO cells After 6 h of CuCl treatment, chosen oxidative stress-related genes were significantly upregulated in HepG2 ATP7B-KO cells, while only HMOX1 showed early induction in HepG2 cells

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doi: 10.1080/02652048.2019.1617363
