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10.1016/j.physbeh.2024.114621 431 ThakurS.DhapolaR.SarmaP.MedhiB.ReddyD
PMCID: PMC22582
XRCC1 protects transcription from toxic PARP1 activity during DNA base excision repair
Mazidi M, Rezaie P, Banach M
Critical safety considerations for laboratory use include potential immunogenicity concernswith peptide therapeutics commonly showing injection site reactions (20-40% with subcutaneous administration) and possible antidrug antibody formationalong with theoretical concerns that pro-angiogenic properties could potentially influence experimental tumor models, requiring appropriate controls in oncology-related research
