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The anxiolytic mechanism of Selank involves modulation of GABAergic neurotransmission through allosteric effects on GABA-A receptor sensitivity, distinct from the direct binding site used by benzodiazepines

49, 249279.10.1146/annurev.arplant.49.1.249 47 NoctorG.GomezL.VanackerH.FoyerC

Lungs Secondary effect Respiratory System Promotes repair of lung tissue and modulates genes involved in pulmonary fibrosis Liver Secondary effect Digestive System Supports hepatic stellate cell remodeling and anti-fibrotic gene expression Frequently Asked Questions

Benzodiazepines and Other CNS Depressants Due to additive pharmacologic effect, the concomitant use of benzodiazepines and other CNS depressants such as benzodiazepines and other sedative/hypnotics, anxiolytics, tranquilizers, muscle relaxants, general anesthetics, antipsychotics, gabapentinoids (gabapentin or pregabalin) and other opioids, including alcohol, can increase the risk of hypotension, respiratory depression, profound sedation, coma, and death

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