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4.6 Heat stress-induced epigenetic modifications Conrad Hal Waddington first coined the term epigenetic to describe the dynamic interaction between an organisms genetic makeup and its environment in shaping observable traits (Waddington, 1956)

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Lifestyle-Related Causes Excessive Screen or Phone Usage Long hours on laptops or phones can strain the neck or wrist nerves, leading to tingling or reduced sensation in the fingers

Imputation was performed with Minimac using the East Asian reference panel from 1000 Genomes phase 1 56

This discrepancy likely reflects challenges for cutaneous penetration of TXA, leading to the development of enhanced delivery systems like liposomes to improve efficacy and tolerability [94]