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[PubMed 23230033] 2895
With DSIP being largely relegated to laboratory use, theres currently no standard protocol for its use among humans
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While embryonic NPCs primarily rely on glycolysis to meet their energy requirements, a metabolic shift toward oxidative phosphorylation (OXPHOS) from stem cells and neural progenitors to mature neurons are critical for proper human neurogenesis and involve specific metabolic regulators, including hexokinase II, lactate dehydrogenase and pyruvate kinase (Wang et al., 2016
