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Garlic: A Review of Potential Therapeutic Effects

Plant isoquinoline alkaloid berberine exhibits chromatin remodeling by modulation of histone deacetylase to induce growth arrest and apoptosis in the a549 cell line

Consistent with this idea, overexpression of dTsc1, dTsc2, the dominant-negative forms of dTOR, or dS6K, all of which are involved in TOR signaling, extended Drosophila lifespan

doi: 10.3390/cells10102603
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