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The SELECT trial (2023) further established semaglutides cardiovascular benefits, showing a 20% reduction in major adverse cardiovascular events in overweight adults with established heart disease even without diabetes

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This process avoids the influence of gastrointestinal tract, liver metabolism and generation of a plethora of numerous metabolites

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Standard formulations or unstable compounds may degrade before the body uses them effectively

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Nature 423 , 545550 (2003)

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