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Upregulation of LOX and LOXL2 has been implicated in several pathologies, including cancer, cardiac fibrosis, idiopathic pulmonary fibrosis, vascular stiffening in aging, and pulmonary hypertension 8,9,10,11,12,13,14

this effect probably depends on gastric ghrelin

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Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium