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Thereby suggesting that Geniposide has protective effect on dopaminergic neurons in substantia nigra of PD mice model induced by MPTP, and its mechanism may be related to the inhibition of neuronal apoptosis (Chen et al., The inhibition of abnormal protein aggregation Currently, impaired degradation of misfolded and aggregated proteins has been proposed to play a key role in the pathogenesis of PD (Le and Chen, 2009)

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References 1.Kahaly G.J., Bartalena L., Hegeds L., Leenhardt L., Poppe K., Pearce S.H