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It inhibits cyclooxygenase (COX) enzymes, the bodys speeders for making pain and swelling chemicals (prostaglandins)
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Because bup/nx has very high opioid receptor affinity, it can precipitate withdrawal in patients who are opioid-intoxicated or in very early withdrawal
12 mg dose = 1.20 mL (120 units)
04 Severe nausea on a new dose Hold at the current dose for an additional 4 weeks before re-attempting escalation
