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This effect was associated with upregulation of hydroxyindole-O-methyltransferase (HIOMT), a key enzyme in melatonin biosynthesis (Khavinson & Anisimov, Neuroendocrinology Letters, 2000)
The nervous system of airways and its remodeling in inflammatory lung diseases
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In adults, insomnia also correlates with severity of ADHD symptoms, highlighting the importance of reducing the overall impact of insomnia when deciding between treatments (Hvolby, 2015)
