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At the cellular level, it promotes collagen synthesis and fibroblast migration, supporting the structural repair of damaged gut tissue
Furthermore, research has shown that specific deletion of the XBP1 gene in oligodendrocytes exacerbates the ERS response, limiting motor function recovery and white matter protection, further demonstrating that the dynamic regulation of ERS in oligodendrocytes is crucial for SCI recovery (Saraswat et al., 2021)

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