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coli killing has been observed in both RAW264.7 cells and mouse peritoneal macrophages (Chaturvedi et al., Phagosomal copper may add to, and perhaps synergize with, the diverse cellular microbial killing strategies described since Elie Metchnikoff's pioneering work on phagocytosis (Gordon, 2008)

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Transcriptional upregulation of SOD , APX , GR , DHAR , and MDHAR genes supported these effects

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This process, by clearing pathogens, inhibiting inflammation, and activating cellular repair pathways, reshapes the structure and function of the gastric mucosal barrier, achieving a transition from destruction-repair to enhancement-homeostasis and providing a new strategy for enhancing the mechanism of the mucus