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The acylated side chain and amino acid substitutions that extend in-vivo half-life also improve storage stability
doi:10.1080/14647273.2018.1494390
Most patients use it once or twice daily depending on concentration
doi: 10.1016/j.ahj.2011.10.002
N Engl J Med 2005;353:24622476.ArticlePubMed 16
