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10.1016/j.cmet.2007.10.002 38

Animal experiments All animals were treated and cared in accordance with the National Institutes of Healths guidelines for the use of experimental animals
Furthermore, testicular cells show much higher amounts of ACE2 than ovarian cells, whereas ovarian cells express considerably lower levels of ACE2 [7,8,9], which may also support higher vulnerability of male gonadal functions including steroidogenesis, towards SARS-CoV-2-mediated impairment

Other challenges in interpreting the data available and designing future studies include the extremely high rate of polypharmacy and substance abuse linked to PED use

Clinical interventions in aging , 1 (4), 307308
