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Hybrid spectral library combining DIA-MS data and a targeted virtual library substantially deepens the proteome coverage

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Per ECHA convention in the DEHP risk assessment, since the main degradation product MEHP is of toxicological relevance, it is not appropriate to calculate the environmental half-life based on primary degradation rates. Reading DOP biodegrades fast as parent disappearance and reading it as full mineralisation through MEHP give two different regulatory verdicts on the same number

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Staresinic, M., Sebecic, B., Patrlj, L., Jadrijevic, S., Suknaic, S., Perovic, D., et al