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doi: 10.3389/fcell.2023.1203708 164
Epigenetic regulation of gene expression occurs via modification of histones and DNA, primarily methylation, which requires methyl groups donated by S -adenosyl methionine, generated via one-carbon metabolism (29)
Metabolites found to be significantly increased in the biofilm compared to suspended culture phenotypes include cysteine-glutathione disulfide (FC = 12.64, p = 3.83 10 -2 ) and glutathione (FC = 3.53, p = 2.66 10 -2 ) which are involved in glutathione metabolism
Y.ZhaoJ.St
Inactivation of human -glutamylcysteine synthetase by cystamine
