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MDSUPDRS motor scores and data on dopaminergic treatment were not available for the subjects covered for the transcriptomics profiling, and therefore the comparison of metabolomics and transcriptomics data focused on the case-control analyses and shared network alterations, confirming the treatment-independence using the metabolomics data (see section on Pathway and network analyses below)

SERM, selective estrogen receptor modulator

Overall, NAC can facilitate alveolar bone regeneration by promoting bone formation and inhibiting bone resorption, thus enabling a positive therapeutic effect for periodontal tissue defects caused by periodontitis

Curr Pharm Des 5:607625 [PubMed] [Google Scholar] Somerville L

HIF2 LSL/LSL , and Vil-ER T2 Cre