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Description
Chelerythrine and Sanguinarine Dock at Distinct Sites on BclXL that Are Not the Classic BH3 Binding Cleft

Levine, A.S
In this context, you can think of a gene as a set of instructions for how to manufacture a particular enzyme

Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer

The authors identify distinct REDOX high and REDOX low classifications in which REDOX high tumors were associated with mutations in KEAP1, NRF2, STK11, and SMARC4 which occurred in 73% of tumors compared to 17% of REDOX low tumors
