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However, lysosomal dysfunction compromises this clearance mechanism, leading to intraneuronal build-up and aggregation of -synuclein 49
doi: 10.3389/fpsyt.2021.585742
B.et al (2019b)
doi: 10.1074/jbc.272.36.22934
The size of the spheroids can be controlled by changing the number of starting cells and this controllability provides convenience for standardized measurement
