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Am J Clin Nutr 110(1):7690 Nazari M, Nikbaf-Shandiz M, Pashayee-Khamene F, Bagheri R, Goudarzi K, Hosseinnia NV et al (2024) Zinc supplementation in individuals with prediabetes and type 2 diabetes: a GRADE-assessed systematic review and dose-response meta-analysis

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et al., 2022) and can reduce intestinal 5-Hydroxytryptamine (5-HT) signaling by lowering tryptophan hydroxylase-1 (TPH1) expression levels, thereby alleviating visceral hypersensitivity (Zhao et al., 2020)

Marquardt RM, Kim TH, Shin J-H, Jeong J-W (2019) Progesterone and estrogen signaling in the endometrium: what goes wrong in endometriosis
As already noted, there are two other modes
