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Randhawa et al., 2005)

Even with IV glutathione, clinical improvements in skin pigmentation are inconsistent and typically modest
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The reaction catalyzed by HO-1 produces three molecules of DDW, and bilirubin acts, like glutathione, to convert H 2 O 2 into DDW

These growth conditions are known to promote the generation of dicarbonyls such as methylglyoxal (Okado-Matsumoto and Fridovich, 2000

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