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Genetic testing for UGT1A1, GSTM1, GSTT1, NAT2, COMT, and SULT1A1 variants helps identify fixed (non-modifiable) conjugation bottlenecks that require lifelong compensatory strategies
Furthermore, we found and reported that GlyNAC supplementation in older adults improved these defects measured at the whole-body level, and also improved cognition [13]
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