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In the face of vitamin B 12 deficiency, conversion of methylmalonyl-CoA to succinyl-CoA cannot take place, which results in accumulation of methylmalonyl-CoA and aberrant fatty acid synthesis

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These injections may also be unsuitable for those with hypovolemic shock or muscle wasting, as these conditions affect drug absorption.

When you rely on oral B12 supplements to improve your B12 levels, you may not get the full benefit of your dosage because the nutrients have to get through your digestive system before they enter your bloodstream

The traditional approach has been: But more recent evidence and updated practices across UK hospitals show that oral B12 works for many patients , if taken in the right dose and form