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New information shows that TNF- also disrupts Leydig cell function, probably contributing to reduced testosterone levels reported in IR injury

1a, Additional file 1: Fig

Some HR characteristics in plants are similar to apoptosis in animal cells such as DNA cleavage, chromatin condensation, cytoplasmic vacuolization and membrane dysfunction (Greenberg and Yao, 2004

doi: 10.1016/j.semcdb.2014.09.002

In further support of the KRAS G13D -specific HER2-HER3 dependence, GSEA of both our RNA-seq data and GSE39582 dataset revealed strong positive enrichment of the PI3K/AKT signaling pathway signature in HER2 high KRAS G13D cases, with notably elevated NES values (Supplementary Fig
