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ChenM.XiaB.ChenB.GuoQ.LiJ.YeM.HuZ.2007N-acetyltransferase 2 slow acetylator genotype associated with adverse effects of sulphasalazine in the treatment of inflammatory bowel disease.213(March 2007),155158,0835-7900 17

Free Radic Biol Med 188:105116

We also observed an increased level of oxidized glutathione (GSSG) in QCG supplemented RBCs after exposure to either Pf CM (1525 mean peak area intensity for 0 M QCG vs 6725 for 1000 M QCG, p = 0.009) ( Figure 5C ) or H 2 O 2 (111,650 mean peak area intensity for 0 M QCG vs 211,245 for 1000 M QCG, p = 0.103) ( Supplemental Figure 2B) compared to RBCs without QCG supplementation or exposure to oxidative stress

This phenomenon can be seen in aging, which is characterized by an overproduction of ROS [86]

References Adamis PDB, Panek AD, Eleutherio ECA (2007) Vacuolar compartmentation of the cadmium-glutathione complex protects Saccharomyces cerevisiae from mutagenesis