vitamin b12 injections versus tablets vs. Supplements: Which Works Best? Vitamin B12 Injections vs. Supplements:

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Biomedical Publications, Davis, CA.] Gullberg, R.G

In the CNS, thiamine deficiency can lead to Wernickes encephalopathy, characterized by nystagmus, ophthalmoplegia, mental status changes, and unsteady stance and gait, due to apoptotic cell death in sensitive brain areas, mainly areas with high metabolic requirement, causing symmetrically distributed lesions among structures such as the third and fourth ventricles, besides dorsomedial thalamus (, , )