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Additionally, the relative mRNA expression of Ppara as well as Ppara- target genes ( Cyp4a10 , Cyp4a14 ) was downregulated in WT mice after treatment with toxic doses of APAP (Fig

Traditionally, CCD has been evaluated using the ergodicity assumption

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Other peptides under investigation Several additional peptides are being studied for disc-related applications, though with less established evidence: Vasoactive Intestinal Peptide (VIP) has demonstrated the ability to slow disc degeneration progression and improve aggrecan levels in mouse studies

[DOI] [PubMed] [Google Scholar] Alvarez-Suarez JM, Giampieri F, Tulipani S, Casoli T, Di Stefano G, Gonzlez-Params AM, Santos-Buelga C, Busco F, Quiles JL, Cordero MD, Bompadre S, Mezzetti B, Battino M