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Tumor necrosis alpha induces coordinated activation of rat GSH synthetic enzymes via NFB and AP-1

(2012) further optimized the hydrogen intervention strategy by comparing the effects of hydrogen water with lactulose (a synthetic disaccharide that generates hydrogen gas through gut microbiota metabolism) in a PD model

This dual dysfunction of microglia and astrocytes leads to extensive oxidative stress, immune activation, and eventual neuronal degradation
