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Age-associated increase in 8-oxo-deoxyguanosine glycosylase/AP lyase activity in rat mitochondria

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Unlike somatic cells, which possess a variety of DNA repair pathways to correct oxidative damage, spermatozoa have only one active DNA repair enzyme, 8-oxoguanine DNA glycosylase (OGG1), which is responsible for repairing oxidative base lesions (73, 74)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Terjung RL, Clarkson P, Eichner ER, Greenhaff PL, Hespel PJ, Israel RG, Kraemer WJ, Meyer RA, Spriet LL, Tarnopolsky MA, Wagenmakers AJ, Williams MH