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PC12-ND6 cells were seeded at a density of 20,000 cells per well in triplicate on poly-d-lysine-coated plates and treated with PBS (control) or NaBt (5 mM) for 24 h at 37 C in 5% CO2 atmosphere

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Several decades ago, studies began emerging that suggested that reduced hyperactivity and impulsivity in stimulant-treated ADHD patients were not paradoxical effects, but in fact also occurred in healthy individuals given the same doses (Rapoport et al., 1978, 1980)

Higher doses mean more gastrointestinal symptoms