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In addition, acylcarnitine accelerates the degradation of the PD1 protein by promoting the acetylation of the E3 ubiquitin ligase FBXO38, revealing not only the mediating role of acylcarnitine in mitochondrial communication between platelets and B cells but also its epigenetic regulatory role in regulating mitochondrial function and PD1 degradation [43]

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Both the chaperone activity and the overall conformation of human PDI are redox-regulated

In-silico, synthesis, characterization, and in-vitro studies on benzylidene-based 2-chloroquinolin derivatives as free radical scavengers in Parkinsons disease