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Changes in antioxidant molecules have been reported even in the early stages of PD

FEBS Lett 472:196202

Shi J, Zhao Y, Wang K, Shi X, Wang Y, Huang H, et al

The midbrains of BER chitosomes group demonstrated a noticeable elevation in the number and size of normal neurons with vesicular nuclei and fewer degenerated neurons and Lewy bodies (Fig

PMID 1262914
